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产品名称： Treg Expansion Kit, mouse130-095-925

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时间： 2017 - 01 - 23

Treg Expansion Kit, mouse130-095-925产品说明Background informationThis kit sustains FoxP3 expression in expanded Treg cells that were previously isolated with the CD4+CD25+ Regulatory T Cell Isolation Kit, mouse. The Treg Expansion Kit is based on MACSiBead™ Particles pre‑loaded with CD3 and CD28 antibodies. Optimal expansion of Treg cells is accomplished by using pre-loaded MACSiBead Particles and Treg cells at a bead-to-cell ratio of 3:1 and recombinant interleukin 2 (rIL-2) at a concentration of ...

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产品名称： Human IFN-γ1b, premium grade130-096-484

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时间： 2017 - 01 - 24

Human IFN-γ1b, premium grade130-096-484产品说明Background informationIFN-γ, the only type II interferon, possesses potent anti-viral activity and immunoregulatory properties. It is structurally unrelated to the type I interferons and binds to a different receptor expressed by most immune cells. IFN-γ is produced predominantly by NK cells and T cells. IFN-γ enhances NK cell and macrophage activity and regulates B cell functions, like immunglobulin production and class switching. In addition, IFN-γ or...

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产品名称： Human SCF, premium grade130-096-695

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时间： 2017 - 01 - 24

Human SCF, premium grade130-096-695产品说明Background informationSCF is a hematopoietic growth factor important for the survival, proliferation, and differentiation of hematopoietic stem cells and progenitor cells. Besides its pivotal role in mast cell development, SCF acts as a potent mast cell chemoattractant and upregulates mast cell adhesion and migration. SCF signals through the c-kit receptor (CD117) and exists in two forms; cell surface bound SCF and soluble SCF. The secreted soluble form of ...

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产品名称： Human IL-12, premium grade130-096-705

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时间： 2017 - 01 - 24

Human IL-12, premium grade130-096-705产品说明Background informationInterleukin 12 (IL-12) is a heterodimeric proinflammatory cytokine and a modulator of cell-mediated immunity, which is mainly produced by macrophages, dendritic cells, and B cells. IL-12 stimulates the production and secretion of several cytokines, in particular IFN-γ, by NK cells and T cells, induces proliferation, and enhances the cytotoxic activity within these cell populations. Another important activity of IL-12, acting together...

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产品名称： Human CD40-Ligand, premium grade130-096-711

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时间： 2017 - 01 - 24

Human CD40-Ligand, premium grade130-096-711产品说明Background informationCD40-Ligand, also known as CD40L, CD154, TRAP, or TNFSF5 is a member of the TNF superfamily transiently expressed on the surface of activated CD4+ T lymphocytes. It is either expressed membrane-bound or proteolytically released as a soluble form which comprises 2/3 of the extracellular domain. Its receptor CD40 is found on antigen-presenting cells such as B cells, dendritic cells, and macrophages. CD40L-CD40 interaction is impo...

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